Xanthine oxidoreductase-IN-4

CAS No. 1026587-58-5

Xanthine oxidoreductase-IN-4( —— )

Catalog No. M36437 CAS No. 1026587-58-5

Xanthine oxidoreductase-IN-4 is an orally active xanthine oxidoreductase (XOR) inhibitor with an IC50 value of 29.3 nM, useful for studying hyperuricemia.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 96 Get Quote
5MG 136 Get Quote
10MG 201 Get Quote
25MG 332 Get Quote
50MG 505 Get Quote
100MG 710 Get Quote
500MG 1467 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Xanthine oxidoreductase-IN-4
  • Note
    Research use only, not for human use.
  • Brief Description
    Xanthine oxidoreductase-IN-4 is an orally active xanthine oxidoreductase (XOR) inhibitor with an IC50 value of 29.3 nM, useful for studying hyperuricemia.
  • Description
    Xanthine oxidoreductase-IN-4 is an orally active xanthine oxidoreductase (XOR) inhibitor. Xanthine oxidoreductase-IN-4 has inhibitory activity against XOR with an IC50 value of 29.3 nM. Xanthine oxidoreductase-IN-4 can be used for the research of hyperuricemia.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Mice acute hyperuricemia modelDosage:5 mg/kg Administration:Oral Result:Reduced serum levels of uric acid significantly from 4 h after administration.
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Xanthine Oxidase (XAO)
  • Recptor
    Xanthine Oxidase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1026587-58-5
  • Formula Weight
    309.32
  • Molecular Formula
    C16H15N5O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(NC1=CC=C(OCC)C=C1)(=O)C2=CC=C(C=C2)C=3NN=NN3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wen Peng, et al. Design, synthesis, and evaluation of tricyclic compounds containing phenyl-tetrazole as XOR inhibitors. Eur J Med Chem. 2022 Nov 28;246:114947. ?
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